IL-18R alpha, Rat (HEK293, Fc)

MedChem Express

IL-18R alpha, Rat (HEK293, Fc)

10

Research Use Only

Il18r1

interleukin 18 receptor 1

interleukin-18 receptor 1, IL18Ralpha2

Interleukin 18 receptor 1

IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor alpha (Ralpha) and beta (Rbeta) chains at the plasma membrane, which induces multiple inflammatory cytokines[1]. IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kbeta- inducing kinase, with subsequent activation of nuclear factor kbeta[2]. IL-18R alpha inhibits the production of IFN-gamma stimulated with the combination of rhIL-2 and rhIL-18[3]. IL-18R alpha Protein, Rat (HEK293, Fc) is a recombinant protein with hFc tag and is produced by HEK293 cells.

41116100

Rat