IL-18R alpha, Rhesus macaque (HEK293, His)

MedChem Express

IL-18R alpha, Rhesus macaque (HEK293, His)

10

Research Use Only

97.00

Interleukin 18 receptor 1

IL-18R alpha (interleukin-18 receptor alpha) is an interleukin receptor of the immunoglobulin superfamily. IL-18 forms a signalling complex with the IL-18 receptor alpha (Ralpha) and beta (Rbeta) chains at the plasma membrane, which induces multiple inflammatory cytokines [1] . IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6, which phosphorylates nuclear factor kbeta- inducing kinase, with subsequent activation of nuclear factor kbeta [2] . IL-18R alpha inhibits the production of IFN-gamma stimulated with the combination of rhIL-2 and rhIL-18 [3] . IL-18R alpha Protein, Cynomolgus (HEK293, His) is a recombinant protein with a His label that consists of 315 amino acids (M1-K315) and is produced by HEK293 cells.

-20°C

12352202