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IL-1RL2, Human (HEK293, Fc)

Name: IL-1RL2, Human (HEK293, Fc)
SKU: HY-P70625_M09
Availability: BackOrder

HY-P70625

Protein IDQ9HB29

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
IL-1RL2, Human (HEK293, Fc)
Delivery Days Customer
10
Certification
Research Use Only
Estimated Purity
97.50
Gene ID8808
Target name
IL1RL2
Target description
interleukin 1 receptor like 2
Target synonyms
IL-1Rrp2, IL-36R, IL1R-rp2, IL1RRP2, interleukin-1 receptor-like 2, IL-1 receptor-related protein 2, IL-36 receptor, interleukin-1 receptor-related protein 2
Protein IDQ9HB29
Protein Name
Interleukin-1 receptor-like 2
Scientific Description
IL-1RL2 Protein, serving as a receptor for interleukin-36 (IL36A, IL36B, and IL36G), forms a complex with the coreceptor IL1RAP, constituting the interleukin-36 receptor. This complex activates NF-kappa-B, MAPK, and other pathways, resembling the IL-1 system. IL-1RL2 is implicated in local inflammatory responses at epithelial barriers, particularly contributing to skin inflammatory reactions by inducing the IL-23/IL-17/IL-22 pathway. IL-1RL2 Protein, Human (HEK293, Fc) is the recombinant human-derived IL-1RL2 protein, expressed by HEK293 , with C-hFc labeled tag.
Storage Instruction
-20°C
UNSPSC
41116100
Species
Human