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IL-23 Responsive STAT3 Luciferase Reporter HEK293 Cell Line

Research Use Only
82591
BPS Bioscience
Product group (Cell) Culture
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    IL-23 Responsive STAT3 Luciferase Reporter HEK293 Cell Line
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    IL-23 Responsive STAT3 Luciferase Reporter HEK293 Cell Line is an engineered HEK293 cell line expressing firefly luciferase under the control of STAT3 response element, and human IL-23 receptor complex (IL12Rbeta1 NM_005535.3 and IL23R NM_144701.3). With this cell line, IL-23 activity can be monitored by measuring luciferase activity. The functionality of the IL-23 Responsive STAT3 Luciferase Reporter HEK293 Cell Line was validated in dose-response assays using a recombinant human interleukin 23 (human IL-23; p19 + p40), inhibition assays using the anti-IL-23 antibodies Ustekinumab and Guselkumab, as well as a Janus Kinase inhibitor, Ruxolitinib.
  • Storage Instruction
    Liquid Nitrogen
  • UNSPSC
    12352207