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IL-36 alpha/IL-1F6, Human

HY-P70702
MedChem Express
Protein IDQ9UHA7
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    IL-36 alpha/IL-1F6, Human (153a.a)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    95.70
  • Protein IDQ9UHA7
  • Protein Name
    Interleukin-36 alpha
  • Scientific Description
    IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-kappaB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases[1]. IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP[2]. IL-36 alpha/IL-1F6 Protein, Human is a recombinant human IL-36 alpha without any tag, which is produced in E. coli.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202

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