IL-36 alpha/IL-1F6, Mouse

MedChem Express

IL-36 alpha/IL-1F6, Mouse

5

Research Use Only

98.00

Il36a

interleukin 36A

Fi; Fil; Fil1; FIL1 epsilon; Fil1epsilon; If36a; IL-1; IL-1 epsilon; Il1f6; IL-1F6; Il1f9; IL-1H1; IL1RP2; interleukin 1 family, member 6 (epsilon); interleukin 1 family, member 9; interleukin-1 epsilon; interleukin-1 family member 6; interleukin-1 homolog 1; interleukin-36 alpha

Interleukin-36 alpha

IL-36 alpha (IL-1F6), a subform of IL-36 family, belongs to IL-1 superfamily. IL-36 alpha mediates inflammatory response. IL-36 alpha binds to IL-36R and activates NF-kappaB and MAPK signaling pathways, but the activation requires N-terminal cleavage by neutrophil granule-derived proteases[1]. IL-36 alpha also binds to IL-1Rrp2 and recruit IL-1RAcP. IL-36 alpha activats the MAPK, Erk1/2 and JNK through IL-36R/IL-1RAcP[2]. IL-36 alpha/IL-1F6 Protein, Mouse is a recombinant mouse IL-36 alpha without any tag, which is produced in E. coli.

-20°C

41116100