IL-5, Human (HEK293, His)

MedChem Express

IL-5, Human (HEK293, His)

10

Research Use Only

98.0

IL5

interleukin 5

B-cell differentiation factor I; colony-stimulating factor, eosinophil; EDF; eosinophil differentiation factor; IL-5; interleukin-5; T-cell replacing factor; TRF

Interleukin-5

The IL-5 Protein, predominantly expressed by T-lymphocytes and NK cells, is crucial for eosinophil survival, differentiation, and chemotaxis. It also affects B-cells, inducing immunoglobulin production, growth, and differentiation. IL-5 Protein activates kinases like LYN, SYK, and JAK2, which signal through RAS-MAPK and JAK-STAT5 pathways. It exists as a disulfide-linked homodimer and interacts with IL5RA and CSF2RB subunits. IL-5 Protein, Human (HEK293, His) is the recombinant human-derived IL-5 protein, expressed by HEK293 , with C-His labeled tag.

-20°C

41116100