WB analysis of human placental tissue lysate using GTX52821 IL15 antibody [13S34].
WB analysis of human placental tissue lysate using GTX52821 IL15 antibody [13S34].
IL15 antibody [13S34]
GTX52821
ApplicationsWestern Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetIL15
Overview
- SupplierGeneTex
- Product NameIL15 antibody [13S34]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID13S34
- Concentration500 ug/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID3600
- Target nameIL15
- Target descriptioninterleukin 15
- Target synonymsIL-15; interleukin-15
- HostMouse
- IsotypeIgG1
- Protein IDP40933
- Protein NameInterleukin-15
- Scientific DescriptionThe protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each others activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203