IL17RA Polyclonal Antibody
RD70354A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetIl17ra
Overview
- SupplierReddot Biotech
- Product NameIL17RA Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.96 mg/ml
- ConjugateUnconjugated
- Gene ID16172
- Target nameIl17ra
- Target descriptioninterleukin 17 receptor A
- Target synonymsAW538159; Cdw217; Il; IL-17 receptor A; Il17r; IL-17RA; interleukin-17 receptor A; VDw21; VDw217
- HostRabbit
- IsotypeIgG
- Scientific DescriptionInterleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203