IL18BP Polyclonal Antibody

Reddot Biotech

IL18BP Polyclonal Antibody

5

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

Research Use Only

1 mg/ml

Unconjugated

IL18BP

interleukin 18 binding protein

FVH; IL18BPa; interleukin-18-binding protein; MC51L-53L-54L homolog gene product; tadekinig-alfa

Rabbit

IgG

The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohns disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Human, Mouse

-20°C

12352203