IL19 antibody [1G54]
GTX52837
ApplicationsWestern Blot, Neutralisation/Blocking
Product group Antibodies
ReactivityHuman
TargetIL19
Overview
- SupplierGeneTex
- Product NameIL19 antibody [1G54]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1G54
- Concentration500 ug/ml
- ConjugateUnconjugated
- Gene ID29949
- Target nameIL19
- Target descriptioninterleukin 19
- Target synonymsIL-10C; interleukin-19; MDA1; melanoma differentiation associated protein-like protein; NG.1; ZMDA1
- HostMouse
- IsotypeIgG2
- Protein IDQ9UHD0
- Protein NameInterleukin-19
- Scientific DescriptionThe protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Osteocytes regulate neutrophil development through IL-19: a potent cytokine for neutropenia treatment. Xiao M et al., 2021 Jun 24, BloodRead more