IL1RAP peptide
GTX26105
Product group Proteins / Signaling Molecules
Overview
- SupplierGeneTex
- Product NameIL1RAP peptide
- Delivery Days Customer9
- CertificationResearch Use Only
- Concentration0.20 mg/ml
- ConjugateUnconjugated
- Scientific DescriptionThe pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAP). IL-1RAP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruits to the IL-1Rcomplex through IL-1RAP. IL-1 activation of stress activated protein kinase and of acid sphingomyelinase also requires IL-1RAP. Like IL-1RI, IL-1RAP subunit is essential for IL-1 mediated cellular response. IL-1RAP is expressed in many tissues.
- Storage Instruction-20°C
- UNSPSC12352202