
WB analysis of HL-60 cell lysate in (A) the absence or (B) the presence of blocking peptide using GTX85088 IL21 antibody. Working concentration : 1 microg/ml
IL21 antibody
GTX85088
Overview
- SupplierGeneTex
- Product NameIL21 antibody
- Delivery Days Customer9
- Antibody SpecificityAt least two isoforms of IL-21 are known to exist; this antibody will detect both isoforms. IL-21 antibody is predicted to not cross-react with other members of the interleukin protein family.
- Application Supplier NoteWB: 1 microg/mL. ICC/IF: 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID59067
- Target nameIL21
- Target descriptioninterleukin 21
- Target synonymsCVID11; IL-21; interleukin-21; Za11
- Protein IDQ9HBE4
- Protein NameInterleukin-21
- Scientific DescriptionA novel cytokine was recently identified in human and mouse and designated IL-21 , which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203