
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA313276(IL21R Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200)
IL21R Antibody
CSB-PA313276
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetIL21R
Overview
- SupplierCusabio
- Product NameIL21R Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID50615
- Target nameIL21R
- Target descriptioninterleukin 21 receptor
- Target synonymsCD360; IL-21 receptor; IMD56; interleukin-21 receptor; NILR; novel interleukin receptor
- HostRabbit
- IsotypeIgG
- Protein IDQ9HBE5
- Protein NameInterleukin-21 receptor
- Scientific DescriptionThe protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203