IL24 Polyclonal Antibody
RD217913A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetIL24
Overview
- SupplierReddot Biotech
- Product NameIL24 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.78 mg/ml
- ConjugateUnconjugated
- Gene ID11009
- Target nameIL24
- Target descriptioninterleukin 24
- Target synonymsC49A; FISP; IL10B; IL-4-induced secreted protein; interleukin-24; MDA7; melanocyte-associated Mda-7; melanoma differentiation-associated gene 7 protein; MOB5; ST16; suppression of tumorigenicity 16 (melanoma differentiation)
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a member of the IL10 family of cytokines. It was identified as a gene induced during terminal differentiation in melanoma cells. The protein encoded by this gene can induce apoptosis selectively in various cancer cells. Overexpression of this gene leads to elevated expression of several GADD family genes, which correlates with the induction of apoptosis. The phosphorylation of mitogen-activated protein kinase 14 (MAPK7/P38), and heat shock 27kDa protein 1 (HSPB2/HSP27) are found to be induced by this gene in melanoma cells, but not in normal immortal melanocytes. Alternatively spliced transcript variants encoding distinct isoforms have been reported.IL24 (Interleukin 24) is a Protein Coding gene. Diseases associated with IL24 include Melanoma and Subclavian Steal Syndrome. Among its related pathways are PEDF Induced Signaling and Immune response IL-23 signaling pathway. GO annotations related to this gene include cytokine activity. An important paralog of this gene is IL20.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203