IL36RN Antibody

Cusabio

IL36RN Antibody

20

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

IL36RN

interleukin 36 receptor antagonist

FIL1, FIL1(DELTA), FIL1D, IL-36Ra, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, PSORS14, interleukin-36 receptor antagonist protein, IL-1 related protein 3, IL-1F5 (IL-1HY1, FIL1-delta, IL-1RP3, IL-1L1, IL-1-delta), IL-1ra homolog 1, IL1F5 (Canonical product IL-1F5a), interleukin 1 family, member 5 (delta), interleukin-1 HY1, interleukin-1 receptor antagonist homolog 1, interleukin-1-like protein 1

Rabbit

IgG

Interleukin-36 receptor antagonist protein

Inhibits the activity of interleukin-36 (IL36A,IL36B and IL36G) by binding to receptor IL1RL2 and preventing its association with the coreceptor IL1RAP for signaling. Part of the IL-36 signaling system that is thought to be present in epithelial barriers and to take part in local inflammatory response; similar to the IL-1 system with which it shares the coreceptor. Proposed to play a role in skin inflammation. May be involved in the innate immune response to fungal pathogens, such as Aspergillus fumigatus. May activate an anti-inflammatory signaling pathway by recruiting SIGIRR.

Human

-20°C or -80°C

41116161