Bio-Connect

IL6 antibody

GTX110527
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetIL6
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL6 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.72 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3569
  • Target name
    IL6
  • Target description
    interleukin 6
  • Target synonyms
    BSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6, interleukin-6, B-cell differentiation factor, B-cell stimulatory factor 2, CTL differentiation factor, hybridoma growth factor, interferon beta-2, interleukin BSF-2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05231
  • Protein Name
    Interleukin-6
  • Scientific Description
    This gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Phan TTT, Truong NV, Wu WG, et al. Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress. Cell Death Discov. 2023,9(1):340. doi: 10.1038/s41420-023-01638-0
    Read this paper
  • Jia L, Jingzhen Z, Xinliang Y, et al. 4-PBA inhibits endoplasmic reticulum stress to improve autophagic flux in the treatment of protamine/lipopolysaccharide-induced interstitial cystitis in rats. Sci Rep. 2023,13(1):14057. doi: 10.1038/s41598-023-38584-x
    Read this paper
  • Ohnishi H, Zhang Z, Yurube T, et al. Anti-Inflammatory Effects of Adiponectin Receptor Agonist AdipoRon against Intervertebral Disc Degeneration. Int J Mol Sci. 2023,24(10). doi: 10.3390/ijms24108566
    Read this paper
  • Chiou WC, Huang GJ, Chang TY, et al. Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway. Biomed Pharmacother. 2023,161:114481. doi: 10.1016/j.biopha.2023.114481
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  • Chini A, Guha P, Malladi VS, et al. Novel long non-coding RNAs associated with inflammation and macrophage activation in human. Sci Rep. 2023,13(1):4036. doi: 10.1038/s41598-023-30568-1
    Read this paper
  • Liang Y, Gu T, Peng S, et al. p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin. Oxid Med Cell Longev. 2022,2022:3415528. doi: 10.1155/2022/3415528
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  • Hsueh YH, Buddhakosai W, Le PN, et al. Therapeutic effect of induced pluripotent stem cell -derived extracellular vesicles in an in vitro and in vivo osteoarthritis model. J Orthop Translat. 2023,38:141-155. doi: 10.1016/j.jot.2022.10.004
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  • Mang Y, Zhang S, Zhao J, et al. Characteristics of pre-sensitization-related acute antibody-mediated rejection in a rat model of orthotopic liver transplantation. Ann Transl Med. 2022,10(19):1066. doi: 10.21037/atm-22-4311
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  • Ko PY, Hsu CC, Chen SY, et al. Cross-Linked Hyaluronate and Corticosteroid Combination Ameliorate the Rat Experimental Tendinopathy through Anti-Senescent and -Apoptotic Effects. Int J Mol Sci. 2022,23(17). doi: 10.3390/ijms23179760
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  • Lai KC, Hong ZX, Hsieh JG, et al. IFIT2-depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice. J Cachexia Sarcopenia Muscle. 2022,13(2):1314-1328. doi: 10.1002/jcsm.12943
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