IL6 antibody
GTX110527
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetIL6
Overview
- SupplierGeneTex
- Product NameIL6 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.72 mg/ml
- ConjugateUnconjugated
- Gene ID3569
- Target nameIL6
- Target descriptioninterleukin 6
- Target synonymsBSF-2, BSF2, CDF, HGF, HSF, IFN-beta-2, IFNB2, IL-6, interleukin-6, B-cell differentiation factor, B-cell stimulatory factor 2, CTL differentiation factor, hybridoma growth factor, interferon beta-2, interleukin BSF-2
- HostRabbit
- IsotypeIgG
- Protein IDP05231
- Protein NameInterleukin-6
- Scientific DescriptionThis gene encodes a cytokine that functions in inflammation and the maturation of B cells. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Phan TTT, Truong NV, Wu WG, et al. Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress. Cell Death Discov. 2023,9(1):340. doi: 10.1038/s41420-023-01638-0Read this paper
- Jia L, Jingzhen Z, Xinliang Y, et al. 4-PBA inhibits endoplasmic reticulum stress to improve autophagic flux in the treatment of protamine/lipopolysaccharide-induced interstitial cystitis in rats. Sci Rep. 2023,13(1):14057. doi: 10.1038/s41598-023-38584-xRead this paper
- Ohnishi H, Zhang Z, Yurube T, et al. Anti-Inflammatory Effects of Adiponectin Receptor Agonist AdipoRon against Intervertebral Disc Degeneration. Int J Mol Sci. 2023,24(10). doi: 10.3390/ijms24108566Read this paper
- Chiou WC, Huang GJ, Chang TY, et al. Ovatodiolide inhibits SARS-CoV-2 replication and ameliorates pulmonary fibrosis through suppression of the TGF-β/TβRs signaling pathway. Biomed Pharmacother. 2023,161:114481. doi: 10.1016/j.biopha.2023.114481Read this paper
- Chini A, Guha P, Malladi VS, et al. Novel long non-coding RNAs associated with inflammation and macrophage activation in human. Sci Rep. 2023,13(1):4036. doi: 10.1038/s41598-023-30568-1Read this paper
- Liang Y, Gu T, Peng S, et al. p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin. Oxid Med Cell Longev. 2022,2022:3415528. doi: 10.1155/2022/3415528Read this paper
- Hsueh YH, Buddhakosai W, Le PN, et al. Therapeutic effect of induced pluripotent stem cell -derived extracellular vesicles in an in vitro and in vivo osteoarthritis model. J Orthop Translat. 2023,38:141-155. doi: 10.1016/j.jot.2022.10.004Read this paper
- Mang Y, Zhang S, Zhao J, et al. Characteristics of pre-sensitization-related acute antibody-mediated rejection in a rat model of orthotopic liver transplantation. Ann Transl Med. 2022,10(19):1066. doi: 10.21037/atm-22-4311Read this paper
- Ko PY, Hsu CC, Chen SY, et al. Cross-Linked Hyaluronate and Corticosteroid Combination Ameliorate the Rat Experimental Tendinopathy through Anti-Senescent and -Apoptotic Effects. Int J Mol Sci. 2022,23(17). doi: 10.3390/ijms23179760Read this paper
- Lai KC, Hong ZX, Hsieh JG, et al. IFIT2-depleted metastatic oral squamous cell carcinoma cells induce muscle atrophy and cancer cachexia in mice. J Cachexia Sarcopenia Muscle. 2022,13(2):1314-1328. doi: 10.1002/jcsm.12943Read this paper

![Sandwich ELISA analysis of serial diluted human IL-6 recombinant protein(50ul per well) using IL6 antibody Coating : GTX15762 IL6 antibody [5IL6] (4 microg/mL) Detection : GTX15761 IL6 antibody [7IL6] (Biotin) (0.035 microg/mL)](https://www.genetex.com/upload/website/prouct_img/normal/GTX15761/GTX15761_63_ELISA_w_23060620_120.webp)
![WB analysis of (1) protein marker, (2) recombinant protein IL6, (3) 293T lysate and (4) SP2/0 lysate using IL6 antibody [1B1-B10-D2] at a concentration of 1microg/ml.](https://www.genetex.com/upload/website/prouct_img/normal/GTX16028/GTX16028_WB_w_23060620_525.webp)
