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IL6 Receptor antibody [B-R6]

GTX76550
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
TargetIL6R
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Overview

  • Supplier
    GeneTex
  • Product Name
    IL6 Receptor antibody [B-R6]
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody recognizes both the soluble and membranous human IL6 Receptor.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    B-R6
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID3570
  • Target name
    IL6R
  • Target description
    interleukin 6 receptor
  • Target synonyms
    CD126; CD126 antigen; gp80; HIES5; IL-1Ra; IL-6 receptor subunit alpha; IL6Q; IL6QTL; IL-6R; IL-6R-1; IL6RA; IL-6RA; IL6RQ; interleukin-6 receptor subunit alpha; membrane glycoprotein 80
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP08887
  • Protein Name
    Interleukin-6 receptor subunit alpha
  • Scientific Description
    This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Osteoarthritic Milieu Affects Adipose-Derived Mesenchymal Stromal Cells. Manferdini C et al., 2020 Feb, J Orthop Res
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