IL6 Receptor antibody [B-R6]
GTX76550
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityHuman
Overview
- SupplierGeneTex
- Product NameIL6 Receptor antibody [B-R6]
- Delivery Days Customer10
- ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDB-R6
- Concentration1 mg/ml
- HostMouse
- IsotypeIgG
- Scientific DescriptionThis gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352203
References
- Osteoarthritic Milieu Affects Adipose-Derived Mesenchymal Stromal Cells. Manferdini C et al., 2020 Feb, J Orthop ResRead more