IL9 Receptor antibody [33423.111]

GeneTex

IL9 Receptor antibody [33423.111]

9

The antibody blocks the cell surface human IL-9 receptor mediated biological activities induced by recombinant human IL-9.

WB: 1-2 microg/ml. ELISA: 0.5-1.0 microg/ml. Neutralizing/Inhibition: 2-4 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

33423.111

Unconjugated

IL9R

interleukin 9 receptor

CD129; IL-9 receptor; IL-9R; interleukin-9 receptor

Mouse

IgG1

Interleukin-9 receptor

Human Interleukin 9 (IL9) was first identified based on its proliferative activity on a human myeloid leukemic cell line. Human IL9 stimulates the proliferation of the human megakaryocytic leukemic cell line M07e. Human IL9 supports erythroid colony formation and synergizes with IL4 in the production of IgE and IgG. The interleukin 9 receptor is a member of the hematopoietin receptor superfamily. The cDNAs encoding mouse and human IL9 receptors have been isolated. The deduced mouse and human transmembrane proteins, sharing 53% amino acid sequence identity, contain 468 and 533 amino acid residues, respectively. A number of isoforms of IL9R, including a putative soluble form, have also been identified. The IL9 receptor is expressed in a variety of hematopoietic cells including T cells, neutrophils, mast cells, and macrophages.

Human

-20°C or -80°C,2°C to 8°C

12352203