Ilepatril [473289-62-2]

MedChem Express

Ilepatril [473289-62-2]

5

473289-62-2

Research Use Only

C22H28N2O5S

432.53

Ilepatril, a dual inhibitor of angiotensin-converting enzyme (ACE) and neutral endopeptidase, has inhibitory effects in the type 2 diabetic nephropathy model in obese Zucker diabetic fatty (ZDF) rats. Ilepatril significantly reduced albuminuria in a dose-dependent manner and may be a strategy distinct from metabolic control to inhibit type 2 diabetic nephropathy[1].

O=C([C@@H]1CCC[C@]2([H])C3=CC=CC=C3C[C@H](NC([C@@H](SC(C)=O)C(C)C)=O)C(N21)=O)O

12131703