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WB analysis of A431 (A), Raji (B), K562 (C) whole cell lysates using GTX55155 ILF3 antibody.
WB analysis of A431 (A), Raji (B), K562 (C) whole cell lysates using GTX55155 ILF3 antibody.
WB analysis of A431 (A), Raji (B), K562 (C) whole cell lysates using GTX55155 ILF3 antibody.

ILF3 antibody

GTX55155
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetILF3
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Overview

  • Supplier
    GeneTex
  • Product Name
    ILF3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID3609
  • Target name
    ILF3
  • Target description
    interleukin enhancer binding factor 3
  • Target synonyms
    CBTF; double-stranded RNA-binding protein, 76 kD; DRBF; DRBP76; dsRNA binding protein NFAR-2/MPP4; interleukin enhancer binding factor 3, 90kD; interleukin enhancer binding factor 3, 90kDa; interleukin enhancer-binding factor 3; M phase phosphoprotein 4, nuclear factor associated with DS RNA; MMP4; M-phase phosphoprotein 4; MPHOSPH4; MPP4; MPP4110; NF110; NF110b; NF90; NF90a; NF90b; NF90c; NF90ctv; NFAR; NFAR-1; NFAR110; NFAR2; NFAR-2; NFAR90; NF-AT-90; nuclear factor associated with dsRNA; nuclear factor of activated T-cells 110 kDa; nuclear factor of activated T-cells 90 kDa; nuclear factor of activated T-cells, 90 kD; TCP110; TCP80; translational control protein 80
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ12906
  • Protein Name
    Interleukin enhancer-binding factor 3
  • Scientific Description
    This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Overexpression of NF90-NF45 Represses Myogenic MicroRNA Biogenesis, Resulting in Development of Skeletal Muscle Atrophy and Centronuclear Muscle Fibers. Todaka H et al., 2015 Jul, Mol Cell Biol
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