Western blot analysis of extracts of various cell lines using ILF3 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using ILF3 Polyclonal Antibody at dilution of 1:1000.
ILF3 Polyclonal Antibody
E-AB-60693
Product group Antibodies
Overview
- SupplierElabscience
- Product NameILF3 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- UNSPSC12352203