iLite® ADCC Target HER2 (-) Assay Ready Cells are depleted of HER2 expression, to be used as an internal control. The control cells can also be used for adjusting background levels when analyzing serum samples, thereby effectively removing any issues with varying background between samples.
iLite ADCC Target HER2 (-) Assay Ready Cells are based on a human embryonic kidney cell line, HEK293*, and have been genetically engineered and optimized to be depleted of HER2 expression.
The cells are to be use as negative controls together with iLite® ADCC Effector (V) Assay Ready Cells and iLite® ADCC Target HER2 (+) Assay Ready Cells for measuring the ADCC activity of anti-HER2 antibodies.
* The HEK-293 cell line has been used under a license obtained from AdVec Inc.
