ILK-IN-2 [1333146-24-9]
HY-18676B
CAS Number1333146-24-9
Product group Chemicals
Estimated Purity99.41
Molecular Weight533.59
Overview
- SupplierMedChem Express
- Product NameILK-IN-2 [1333146-24-9]
- Delivery Days Customer5
- CAS Number1333146-24-9
- CertificationResearch Use Only
- Estimated Purity99.41
- Molecular FormulaC30H30F3N5O
- Molecular Weight533.59
- Scientific DescriptionILK-IN-2 (OSU-T315 analog) is an oral PDK2 inhibitor and also an ILK inhibitor, with an IC50 of 0.6 microM. ILK-IN-2 induces cell autophagy and apoptosis, showing anti-tumor activity. ILK-IN-2 directly abolishes AKT activation by preventing AKT from translocating to lipid rafts, triggering Caspase-dependent apoptosis in chronic lymphocytic leukemia (CLL) and extending the lifespan in TCL1 mouse models[1][2].
- SMILESO=C(NC)CCC1=NN(C2=CC=C(N3CCNCC3)C=C2)C(C4=CC=C(C5=CC=C(C(F)(F)F)C=C5)C=C4)=C1
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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Product group Chemicals
CAS Number1333146-24-9
Molecular Weight533.59
- SizePrice
Product group Chemicals
ILK-IN-2ORB1301749
CAS Number1333146-24-9
Estimated Purity99.31%
Molecular Weight533.59
- SizePrice