Imidazole ketone erastin

AbMole BioScience

Imidazole ketone erastin

9

1801530-11-9

Chemical

Research Use Only

C35H35ClN6O5

655.14

Imidazole Ketone Erastin (IKE) is an inducer for ferroptosis iron death. It is also a potent, selective, and metabolically stable system XC -- inhibitor. IKE is more water-soluble than Erastin. Inducing iron death in diffuse large B-cell lymphoma cells (e.g. Sudhl-5/6/16).

CC(C)OC1=CC=C(C=C1N2C(=NC3=CC=CC=C3C2=O)CN4CCN(CC4)C(=O)COC5=CC=C(Cl)C=C5)C(=O)C[N]6C=CN=C6

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