Imidazole ketone erastin [1801530-11-9]

AbMole BioScience

Imidazole ketone erastin [1801530-11-9]

7

1801530-11-9

Research Use Only

99.82%

C35H35ClN6O5

655.14

Imidazole Ketone Erastin (IKE) is an inducer for ferroptosis iron death. It is also a potent, selective, and metabolically stable system XC -- inhibitor. IKE is more water-soluble than Erastin. Inducing iron death in diffuse large B-cell lymphoma cells (e.g. Sudhl-5/6/16).

CC(C)OC1=CC=C(C=C1N2C(=NC3=CC=CC=C3C2=O)CN4CCN(CC4)C(=O)COC5=CC=C(Cl)C=C5)C(=O)C[N]6C=CN=C6

-20°C

12161500