
Western blot All lanes: IMPACT antibody at 10microg/ml Lane 1: Hela whole cell lysate Lane 2: HL60 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 37, 23 kDa Observed band size: 37, 52 kDa
IMPACT Antibody
CSB-PA889191LA01HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetIMPACT
Overview
- SupplierCusabio
- Product NameIMPACT Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID55364
- Target nameIMPACT
- Target descriptionimpact RWD domain protein
- Target synonymsRWDD5, protein IMPACT, Impact homolog, RWD domain containing 5, imprinted and ancient gene protein homolog
- HostRabbit
- IsotypeIgG
- Protein IDQ9P2X3
- Protein NameProtein IMPACT
- Scientific DescriptionTranslational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its action on GCN2, may also facilitate neuritogenesis.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161





