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Incadronate (disodium) [138330-18-4]

HY-B2097
MedChem Express
CAS Number138330-18-4
Product group Chemicals
Molecular Weight331.15
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Incadronate (disodium) [138330-18-4]
  • Delivery Days Customer
    5
  • CAS Number
    138330-18-4
  • Certification
    Research Use Only
  • Molecular Formula
    C8H17NNa2O6P2
  • Molecular Weight
    331.15
  • Scientific Description
    Incadronate disodium (YM 175) is a bisphosphonate with strong inhibitory activity on bone resorption. Incadronate disodium indirectly stimulates renal 25-hydroxyvitamin D-1-hydroxylase by increasing circulating parathyroid hormone. Incadronate disodium, a cholesterol-lowering agent, is a potent inhibitor of rat liver microsomal squalene synthase (Ki=57 nM). Incadronate disodium inhibits sterol biosynthesis in mouse macrophage J774 cells (IC50=64 microM). Incadronate disodium has the potential for malignant tumors research[1][2][3].
  • SMILES
    O=P(C(P(O)(O[Na])=O)NC1CCCCCC1)(O[Na])O
  • UNSPSC
    12352200