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Incadronic acid [124351-85-5]

HY-149149
MedChem Express
CAS Number124351-85-5
Product group Chemicals
Estimated Purity98.03
Molecular Weight287.19
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Incadronic acid [124351-85-5]
  • Delivery Days Customer
    5
  • CAS Number
    124351-85-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.03
  • Molecular Formula
    C8H19NO6P2
  • Molecular Weight
    287.19
  • Scientific Description
    Incadronic acid inhibits growth of Dictyostelium discoideum with an IC50 of 1.6 microM. Incadronic acid binds the farnesyl diphosphate synthase (FPPS) in Leishmania major with the Ki of 23 nM. Incadronic acid inhibits the bone resorption and reduces bone loss, that can be used in osteoporosis research. Incadronic acid inhibits the proliferation of cells RAW264.7, PC-3 and MCF-7 with IC50 of 48 to 228.6 microM[1].
  • SMILES
    O=P(O)(C(P(O)(O)=O)NC1CCCCCC1)O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12131703