INCB3344 R-isomer
HY-50674A
Overview
- SupplierMedChem Express
- Product NameINCB3344 R-isomer
- Delivery Days Customer10
- Estimated Purity95.02%
- Molecular FormulaC29H34F3N3O6
- Molecular Weight577.59
- Scientific DescriptionINCB3344 R-isomer is the R-isomer of INCB3344. INCB3344 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 values of 5.1 nM (hCCR2) and 9.5 nM (mCCR2) in binding antagonism and 3.8 nM (hCCR2) and 7.8 nM (mCCR2) in antagonism of chemotaxis activity.
- SMILESCCO[C@H]1CN([C@]2([H])CC[C@](C3=CC(OCO4)=C4C=C3)(O)CC2)C[C@@H]1NC(CNC(C5=CC(C(F)(F)F)=CC=C5)=O)=O
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200