Indirubin-3-oxime
E0072
Estimated Purity...
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameIndirubin-3-oxime [667463-82-3]
- Delivery Days Customer9
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionIndirubin-3-oxime (IDR3O, I3O) is an indirubin analogue that shows favorable inhibitory activity targeting GSK-3beta and CDKs. Indirubin-3-oxime also inhibits JNKs with IC50s of 0.8 microM, 1.4 microM, and 1.0 microM for JNK1, JNK2, and JNK3, respectively. Indirubin-3-oxime activates Wnt/beta-catenin signaling and inhibits adipocyte differentiation and obesity.
- UNSPSC51202000