Indirubin-5-sulfonate [244021-67-8]

MedChem Express

Indirubin-5-sulfonate [244021-67-8]

10

244021-67-8

Research Use Only

C16H10N2O5S

342.33

Indirubin-5-sulfonate is a cyclin-dependent kinase (CDK) inhibitor, with IC50 values of 55 nM, 35 nM, 150 nM, 300 nM and 65 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E, CDK4/cyclin D1, and CDK5/p35, respectively[1]. Indirubin-5-sulfonate also shows inhibitory activity against GSK-3beta[2].

O=S(C1=CC2=C(NC(/C2=C3NC4=C(C=CC=C4)C/3=O)=O)C=C1)(O)=O

12352200