(-)-Indolactam V

MedChem Express

(-)-Indolactam V [90365-57-4]

5

90365-57-4

Research Use Only

98.75

C17H23N3O2

301.38

(-)-Indolactam V is a PKC activator, with K i s of 3.36 nM, 1.03 microM for eta-CRD2 (PKCeta surrogate peptide), gamma-CRD2 (PKCgamma surrogate peptide), and K d s of 5.5 nM (eta-C1B), 7.7 nM (epsilon-C1B), 8.3 nM (delta-C1B), 18.9 nM (beta-C1A-long), 20.8 nM (alpha-C1A-long), 137 nM (beta-C1B), 138 nM (gamma-C1A), 213 nM (gamma-C1B), and has antitumor activity.

CC(C)[C@@H](C1=O)N(C)C2=C3C(NC=C3C[C@H](N1)CO)=CC=C2

-20°C,2°C to 8°C

12352200