Indotecan [915303-09-2]

MedChem Express

Indotecan [915303-09-2]

5

915303-09-2

Research Use Only

98.0

C26H26N2O7

478.49

Indotecan (LMP-400), an indenoisoquinoline derivative, is a potent Topoisomerase I inhibitor, with IC50s of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively. Indotecan prevents the relaxation of supercoiled DNA and can be used for the research of visceral leishmaniasis[1][2].

O=C1C2=CC(OC)=C(OC)C=C2C3=C(C(C=C(OCO4)C4=C5)=C5C3=O)N1CCCN6CCOCC6

2°C to 8°C

12352200