Inflachromene [908568-01-4]

TargetMol Chemicals

Inflachromene [908568-01-4]

10

908568-01-4

Chemical

Research Use Only

Inflachromene

99.88%

C21H19N3O4

377.39

Inflachromene (ICM) is an inhibitor of HMGB1 and HMGB expression with anti-inflammatory activity.Inflachromene reduces seizure severity in a mouse model of epilepsy by inhibiting HMGB1 translocation, inhibits endothelial proliferation through the HMGB1/2-regulated TLR4-NF-kappaB pathway, and inhibits autophagy by regulating Beclin 1 activity. Inflachromene can be used to study epilepsy.

3 years

CC1(C)Oc2cc(O)ccc2C2C1=CCn1n2c(=O)n(-c2ccccc2)c1=O

-20°C

12352200