Influenza A [A/Shanghai/2/2013(H7N9)] Hemagglutinin (HA) Protein, Fc Tag

ACRObiosystems

Influenza A [A/Shanghai/2/2013(H7N9)] Hemagglutinin (HA) Protein, Fc Tag

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Viral Proteins

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Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 82.5 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Description: Neuraminidase (NA) and hemagglutinin (HA) are major membrane glycoproteins found on the surface of influenza virus. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle. Hemagglutinin also plays a major role in the determination of host range restriction and virulence. As a class I viral fusion protein, hemagglutinin is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Influenza A [A/Shanghai/2/2013(H7N9)] HA, Fc Tag (HA9-V5253) is expressed from human 293 cells (HEK293). It contains AA Asp 19 - Gly 338, Leu 341 - Asp 523 (Accession # R4NN21-1).

-20℃

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