Influenza A virus NS2 / NEP antibody
GTX125953
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityVirus
Overview
- SupplierGeneTex
- Product NameInfluenza A virus NS2 / NEP antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionInfluenza A viruses are single stranded, negative sense RNA viruses. Two distinct non-structural proteins NS1 and NS2 are translated from one of the eight RNA segments by using different reading frames.The influenza A virus NS2 is located in the nucleus and the cytoplasm. NS2 is essential for nuclear export of influenza virus ribonucleoprotein (RNP) complexes.
- ReactivityVirus
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Yang Q, Elz AE, Panis M, et al. Modulation of Influenza A virus NS1 expression reveals prioritization of host response antagonism at single-cell resolution. Front Microbiol. 2023,14:1267078. doi: 10.3389/fmicb.2023.1267078Read this paper
- Zhang L, Wang Y, Shao Y, et al. Fine Regulation of Influenza Virus RNA Transcription and Replication by Stoichiometric Changes in Viral NS1 and NS2 Proteins. J Virol. 2023,97(5):e0033723. doi: 10.1128/jvi.00337-23Read this paper
- Zhu Y, Wang R, Zou J, et al. N6-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication. PLoS Pathog. 2023,19(4):e1011305. doi: 10.1371/journal.ppat.1011305Read this paper
- Zhang B, Liu M, Huang J, et al. H1N1 Influenza A Virus Protein NS2 Inhibits Innate Immune Response by Targeting IRF7. Viruses. 2022,14(11). doi: 10.3390/v14112411Read this paper
- Zhu Y, Wang R, Yu L, et al. Human TRA2A determines influenza A virus host adaptation by regulating viral mRNA splicing. Sci Adv. 2020,6(25):eaaz5764. doi: 10.1126/sciadv.aaz5764Read this paper
- Zhang X, Xia Y, Yang L, et al. Brevilin A, a Sesquiterpene Lactone, Inhibits the Replication of Influenza A Virus In Vitro and In Vivo. Viruses. 2019,11(9). doi: 10.3390/v11090835Read this paper
- Choi JG, Kim YS, Kim JH, et al. Antiviral activity of ethanol extract of Geranii Herba and its components against influenza viruses via neuraminidase inhibition. Sci Rep. 2019,9(1):12132. doi: 10.1038/s41598-019-48430-8Read this paper
- Ren X, Yu Y, Li H, et al. Avian Influenza A Virus Polymerase Recruits Cellular RNA Helicase eIF4A3 to Promote Viral mRNA Splicing and Spliced mRNA Nuclear Export. Front Microbiol. 2019,10:1625. doi: 10.3389/fmicb.2019.01625Read this paper
- Holzberg M, Boergeling Y, Schräder T, et al. Vemurafenib Limits Influenza A Virus Propagation by Targeting Multiple Signaling Pathways. Front Microbiol. 2017,8:2426. doi: 10.3389/fmicb.2017.02426Read this paper
- Chutiwitoonchai N, Mano T, Kakisaka M, et al. Inhibition of CRM1-mediated nuclear export of influenza A nucleoprotein and nuclear export protein as a novel target for antiviral drug development. Virology. 2017,507:32-39. doi: 10.1016/j.virol.2017.04.001Read this paper