Ingenol 3,20-dibenzoate

MedChem Express

Ingenol 3,20-dibenzoate [59086-90-7]

10

59086-90-7

Research Use Only

99.96

C34H36O7

556.65

Ingenol 3,20-dibenzoate is a potent protein kinase C (PKC) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-gamma production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells [1] [2] .

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-20°C

12352200