Bio-Connect

INK4C-IN-2 [6314-70-1]

HY-108420
MedChem Express
CAS Number6314-70-1
Product group Chemicals
Estimated Purity98.10
Molecular Weight283.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    INK4C-IN-2 [6314-70-1]
  • Delivery Days Customer
    5
  • CAS Number
    6314-70-1
  • Certification
    Research Use Only
  • Estimated Purity
    98.10
  • Molecular Formula
    C13H17NO4S
  • Molecular Weight
    283.34
  • Scientific Description
    INK4C-IN-2 (Compound 40) is the inhibitor for INK4C (also known as p18) and the activator for CDK4/6. INK4C-IN-2 increases the number and expansion capacity of mouse and human hematopoietic stem cells (HSCs) with EC50 of 5.21 nM, promotes the self-renewal and multilineage differentiation of HSCs. INK4C-IN-2 improves the expansion and long-term hematopoietic reconstruction ability of HSCs in mouse bone marrow transplantation model[1].
  • SMILES
    O=C(O)C1=CC=C(S(=O)(NC2CCCCC2)=O)C=C1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200