
Western Blot Positive WB detected in: HepG2 whole cell lysate All lanes: INO80 antibody at 2.9ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 177 kDa Observed band size: 177 kDa
INO80 Antibody
CSB-PA892466LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
TargetINO80
Overview
- SupplierCusabio
- Product NameINO80 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID54617
- Target nameINO80
- Target descriptionINO80 complex ATPase subunit
- Target synonymschromatin-remodeling ATPase INO80; DNA helicase INO80; DNA helicase-related INO80 complex homolog 1; DNA helicase-related protein INO80; homolog of yeast INO80; INO80 complex subunit A; INO80A; INOC1; putative DNA helicase INO80 complex homolog 1
- HostRabbit
- IsotypeIgG
- Protein IDQ9ULG1
- Protein NameChromatin-remodeling ATPase INO80
- Scientific DescriptionATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair (PubMed:16230350, PubMed:16298340, PubMed:17721549, PubMed:20855601, PubMed:20237820). Binds DNA (PubMed:16298340, PubMed:21303910). As part of the INO80 complex, remodels chromatin by shifting nucleosomes (PubMed:16230350, PubMed:21303910). Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator (PubMed:17721549). Involved in UV-damage excision DNA repair (PubMed:20855601). The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation (PubMed:20687897). Involved in DNA replication (PubMed:20237820). Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle (PubMed:20237820).
- Storage Instruction-20°C or -80°C
- UNSPSC12352203