Inotilone

MedChem Express

Inotilone [906366-79-8]

14

906366-79-8

Research Use Only

C12H10O4

218.21

Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9 , to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IkappaBalpha phosphorylation and NFkappaB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFkappaB pathways [1] .

O=C1/C(OC(C)=C1)=C/C2=CC=C(O)C(O)=C2

2°C to 8°C

12352200