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Inotilone

HY-111172
MedChem Express
CAS Number906366-79-8
DownloadMSDS
Product group Chemicals
Molecular Weight218.21
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Inotilone [906366-79-8]
  • Delivery Days Customer
    14
  • CAS Number
    906366-79-8
  • Certification
    Research Use Only
  • Molecular Formula
    C12H10O4
  • Molecular Weight
    218.21
  • Scientific Description
    Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9 , to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IkappaBalpha phosphorylation and NFkappaB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFkappaB pathways [1] .
  • SMILES
    O=C1/C(OC(C)=C1)=C/C2=CC=C(O)C(O)=C2
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200