Inotodiol [35963-37-2]

MedChem Express

Inotodiol [35963-37-2]

5

35963-37-2

Research Use Only

98.29

C30H50O2

442.72

Inotodiol activates p53 signaling pathway, inhibits MMP-2/9, and exhibits antitumor activity in cancer cell HeLa. Inotodiol inhibits the generation of ROS and exhibits antioxidant and neuroprotective effects. Inotodiol inhibits the activation of MAPK and NF-kappaB signaling pathway, and exhibits anti-inflammatory activity. Inotodiol inhibits TLR-4 mediated TNF-alpha production (IC50s in BMMC and BMDM is 0.7 microM and 3.0 microM), inhibits the degranulation in mast cell, exhibits anti-allergic activity. Inotodiol is orally active[1][2][3][4][5].

C[C@@]1(CC[C@@H]2O)C(CC[C@@]34C)=C(CC[C@@]1([H])C2(C)C)[C@@]3(CC[C@]4([H])[C@H](C)[C@H](O)C/C=C(C)\C)C

2°C to 8°C

12352200