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ProductsBack/INSM1 antibody [A-8]

INSM1 antibody [A-8]

Research Use Only
GTX01723
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetINSM1
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Overview

  • Supplier
    GeneTex
  • Product Name
    INSM1 antibody [A-8]
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    A-8
  • Concentration
    0.1 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID3642
  • Target name
    INSM1
  • Target description
    INSM transcriptional repressor 1
  • Target synonyms
    IA1; IA-1; insulinoma-associated 1; insulinoma-associated protein 1; zinc finger protein IA-1
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDQ01101
  • Protein Name
    Insulinoma-associated protein 1
  • Scientific Description
    Insulinoma-associated 1 (INSM1) gene is intronless and encodes a protein containing both a zinc finger DNA-binding domain and a putative prohormone domain. This gene is a sensitive marker for neuroendocrine differentiation of human lung tumors. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • INSM1 expression in a subset of thoracic malignancies and small round cell tumors: rare potential pitfalls for small cell carcinoma. Tsai HK et al., 2020 Aug, Mod Pathol
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  • Diagnostic Value of Insulinoma-Associated Protein 1 (INSM1) and Comparison With Established Neuroendocrine Markers in Pulmonary Cancers. Staaf J et al., 2020 Sep 1, Arch Pathol Lab Med
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  • Establishment and characterization of a novel neuroendocrine carcinoma cell line derived from a human ascending colon tumor. Shinji S et al., 2019 Dec, Cancer Sci
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  • Triple marker composed of p16, CD56, and TTF1 shows higher sensitivity than INSM1 for diagnosis of pulmonary small cell carcinoma: proposal for a rational immunohistochemical algorithm for diagnosis of small cell carcinoma in small biopsy and cytology specimens. Svajdler M et al., 2019 Mar, Hum Pathol
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  • Insulinoma-associated protein 1 (INSM1) is a sensitive and highly specific marker of neuroendocrine differentiation in primary lung neoplasms: an immunohistochemical study of 345 cases, including 292 whole-tissue sections. Mukhopadhyay S et al., 2019 Jan, Mod Pathol
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