Various tissue extracts (50 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Insulin Receptor Beta antibody [HL2737] (GTX639566) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident femto Western HRP Substrate.
![Insulin Receptor beta antibody [HL2737] detects Insulin Receptor beta protein at cell membrane and cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human pancreatic cancer. Insulin Receptor beta stained by Insulin Receptor beta antibody [HL2737] (GTX639566) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min](https://www.genetex.com/upload/website/prouct_img/normal/GTX639566/GTX639566_T-45271_20240111_IHC-P_24012217_456.webp "Insulin Receptor beta antibody [HL2737] detects Insulin Receptor beta protein at cell membrane and cytoplasm by immunohistochemical analysis. Sample: Paraffin-embedded human pancreatic cancer. Insulin Receptor beta stained by Insulin Receptor beta antibody [HL2737] (GTX639566) diluted at 1:100. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min")
![Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Insulin Receptor Beta antibody [HL2737] (GTX639566) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.](https://www.genetex.com/upload/website/prouct_img/normal/GTX639566/GTX639566_45355_20240322_WB_TPM_watermark_24032600_798.webp "Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Insulin Receptor Beta antibody [HL2737] (GTX639566) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.")
Various tissue extracts (50 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with Insulin Receptor Beta antibody [HL2737] (GTX639566) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident femto Western HRP Substrate.
Insulin Receptor beta antibody [HL2737]
GTX639566
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetINSR
Overview
- SupplierGeneTex
- Product NameInsulin Receptor beta antibody [HL2737]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDHL2737
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID3643
- Target nameINSR
- Target descriptioninsulin receptor
- Target synonymsCD220, HHF5, insulin receptor, IR
- HostRabbit
- IsotypeIgG
- Protein IDP06213
- Protein NameInsulin receptor
- Scientific DescriptionThis gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
Datasheet
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