FACS analysis of human peripheral blood lymphocytes using GTX01494-08 Integrin alpha 4 antibody [9F10] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.25 microg (5 microl)
FACS analysis of human peripheral blood lymphocytes using GTX01494-08 Integrin alpha 4 antibody [9F10] (PE). Solid lone : primary antibody Dashed line : isotype control antibody amount : 0.25 microg (5 microl)
Integrin alpha 4 antibody [9F10] (PE)
GTX01494-08
ApplicationsFlow Cytometry
Product group Antibodies
TargetITGA4
Overview
- SupplierGeneTex
- Product NameIntegrin alpha 4 antibody [9F10] (PE)
- Delivery Days Customer9
- Application Supplier NoteFACS: 0.25 microg (5 microl) for 105-108 cells in 100 microl sample per test. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID9F10
- Concentration0.05 mg/ml
- ConjugateRPE
- Gene ID3676
- Target nameITGA4
- Target descriptionintegrin subunit alpha 4
- Target synonymsCD49D, IA4, integrin alpha-4, 269C wild type, CD49 antigen-like family member D, VLA-4 subunit alpha, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, integrin alpha-IV, very late activation protein 4 receptor, alpha 4 subunit
- HostMouse
- IsotypeIgG1
- Protein IDP13612
- Protein NameIntegrin alpha-4
- Scientific DescriptionThe gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohns disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
- Storage Instruction2°C to 8°C
- UNSPSC12352203
References
- Ellis-Connell AL, Balgeman AJ, Zarbock KR, et al. ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment. J Virol. 2018,92(3). doi: 10.1128/JVI.01748-17Read this paper
Datasheet
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