Integrin alpha 4 antibody [HP2.1]

GeneTex

Integrin alpha 4 antibody [HP2.1]

9

The molecular weight of the recognized antigen is 150 kDa. CD49d antigen is the integrin alpha-4 chain non-covalently associated with the integrin beta-1-chain (CD29 molecule) forming the VLA4 complex. Reacts with monocytes, T cells, B cells, thymocytes a

*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, Other Application

Research Use Only

Monoclonal

HP2.1

0.20 mg/ml

Unconjugated

ITGA4

integrin subunit alpha 4

269C wild type; alpha 4 subunit of VLA-4 receptor; antigen CD49D, alpha-4 subunit of VLA-4 receptor; CD49 antigen-like family member D; CD49D; IA4; integrin alpha-4; integrin alpha-IV; very late activation protein 4 receptor, alpha 4 subunit; VLA-4 subunit alpha

Mouse

IgG1

Integrin alpha-4

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohns disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Human

2°C to 8°C

12352203