Integrin alpha 6 antibody [NKI-GoH3] (PE)

GeneTex

Integrin alpha 6 antibody [NKI-GoH3] (PE)

7

FACS: 10 microL reagent / 100 microL of whole blood or 106 cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Research Use Only

Monoclonal

NKI-GoH3

RPE

ITGA6

integrin subunit alpha 6

CD49 antigen-like family member F; CD49f; integrin alpha-6; integrin alpha6B; integrin, alpha 6; ITGA6B; VLA-6

Rat

IgG2a

Integrin alpha-6

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

2°C to 8°C

12352203