WB analysis of various sample lysates using GTX66156 Integrin alpha 8 antibody. Dilution : 1:3000 Loading : 25microg per lane
Integrin alpha 8 antibody
GTX66156
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetITGA8
Overview
- SupplierGeneTex
- Product NameIntegrin alpha 8 antibody
- Delivery Days Customer9
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID8516
- Target nameITGA8
- Target descriptionintegrin subunit alpha 8
- Target synonymsintegrin alpha-8; integrin, alpha 8
- HostRabbit
- IsotypeIgG
- Scientific DescriptionIntegrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Apr 2014]
- ReactivityHuman, Mouse, Rat
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203