
WB analysis of serum-starved mitotic HeLa cells generated by treatment with 100 ng/mL taxol for 16 hours using GTX25189 Integrin beta 1 / CD29 (phospho Thr788/Thr789) antibody. The data show that only the immunogen phosphopeptide blocks the signal, demonstrating the specificity of the antibody. The membrane treated with phosphatase (Lane 5) eliminates the signal further verifying that the antibody is phospho-specific.
Integrin beta 1 / CD29 (phospho Thr788/Thr789) antibody
GTX25189
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityFeline, Human, Mouse
TargetITGB1
Overview
- SupplierGeneTex
- Product NameIntegrin beta 1 / CD29 (phospho Thr788/Thr789) antibody - Orthogonal Validated
- Delivery Days Customer9
- Application Supplier NoteWB: 1:250. ICC/IF: 1:250. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID3688
- Target nameITGB1
- Target descriptionintegrin subunit beta 1
- Target synonymsCD29; FNRB; glycoprotein IIa; GPIIA; integrin beta 1; integrin beta-1; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); MDF2; MSK12; very late activation protein, beta polypeptide; VLAB; VLA-BETA
- HostRabbit
- IsotypeIgG
- Protein IDP05556
- Protein NameIntegrin beta-1
- Scientific DescriptionIntegrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- ReactivityFeline, Human, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Synthesis and anti-metastatic effects of pregn-17(20)-en-3-amine derivatives. Qin N et al., 2016 Nov 29, Eur J Med ChemRead more