Intoplicine [125974-72-3]

MedChem Express

Intoplicine [125974-72-3]

10

125974-72-3

Research Use Only

98.36

C21H24N4O

348.44

Intoplicine (RP 60475), an antitumor derivative in the 7H-benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase I and II inhibitor. Intoplicine strongly binds DNA (KA = 2 x 105 /M) and thereby increases the length of linear DNA[1][2].

OC1=CC=C2C3=C(NC4=C3C(NCCCN(C)C)=NC=C4C)C=CC2=C1

2°C to 8°C

12352200