Intoplicine (dimesylate)

MedChem Express

Intoplicine (dimesylate) [133711-99-6]

10

133711-99-6

Research Use Only

98.28

C23H32N4O7S2

540.65

Intoplicine (RP 60475) dimesylate, an antitumor derivative in the 7H-benzo[e]pyrido[4,3-b]indole series, is a DNA topoisomerase I and II inhibitor. Intoplicine dimesylate strongly binds DNA (K A = 2 x 10 5 /M) and thereby increases the length of linear DNA [1] [2] .

OC1=CC=C2C3=C(NC4=C3C(NCCCN(C)C)=NC=C4C)C=CC2=C1.CS(O)(=O)=O.CS(O)(=O)=O

2°C to 8°C

12352200